Sickle Cell Punnett Square help!!!!?
If two individuals are heterozygous for the hemoglobin sickle cell allele, what is the probability that their offspring will have full-blown sickle cell anemia? Please use a Punnett Square to demonstrate your work. I would greatly appreciate your help with this. Thank you! 😊
6 Answers
Lets say;
normal gene = S
sickle cell gene =s
So a heterozygous person = Ss
Punnett square for offspring between two heterozygous people :
| S | s |
——+——–+———
S | SS | Ss |
——+——–+———-
s | Ss | ss |
—————————-
So from this you can see that 1/4 (25%) gets ss, i.e. 25% have full blown sickle cell anemia
50% will be heterozygous and the remaining 25% will be normal
Feb 09, 2025
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Sickle Cell Punnett Square help!!!!?
If two individuals who are heterozygous for the hemoglobin sickle cell allele produce an offspring, what is the probability that the offspring will have full blown sickle cell anemia? (Use a Punnett Square to show your work)
HOW DO YOU DO THIS??
Please help I will love you forever ?
That is true for same size populations. To know the expected values of incidence, that are 1/12 for Carriers and 1/500 for infected (http://www.cdc.gov/ncbddd/sicklecell/data.html), you also need to account the following formula: F(SS)+2*F(Ss)+F(ss)=1, so solving it with the real incidence you have F(SS)+1/12+1/500=1, this means that you have in reality the following probability for the general population: AA = 91,5%, Ss or sS = 8,3% and finally ss = 0,2%, and those are the probabilities that really matter…
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