What is the correct order of a signal being transmitted across a neuromuscular junction?

Question

What is the correct sequence in which a signal is transmitted across a neuromuscular junction?

Theresa Wehner · Accepted Answer

The correct order is:Ion channels - synaptic vesicle - neurotransmitter - end plate potential.Explanation: A neuromuscular junction is the point where a motor neuron meets with a skeletal muscle fiber which it innervates. It is the site where a chemical interaction or communication between a motor neuron and a muscle cell occurs. For transmission of impulses to occur between a neuron and a muscle cell, an action potential from the motor neuron travels along the axon of the neuron to the presynaptic terminal of the neuron where it activates voltage gated calcium ion channels which causes the influx of calcium ions into the intracellular space of the neuron. The calcium ions bind to the sensor proteins that are located on the synaptic vesicles and trigger the release of the neurotransmitter into the synaptic cleft. The neurotransmitter moves from the synaptic cleft and binds to its receptors on the postsynaptic membrane of the muscle cell. The binding of the neurotransmitter to its receptors creates end plate potential which causes the skeletal muscle fibers to depolarise.

Anonymous · Answer

The neuromuscular junction (NMJ) is the site of communication, a chemical synapse, between motor nerve axons and muscle fibers. This junction transmit ssignals from the motor neuron to the skeletal muscle fibre quickly and reliably. The goal is to ensure precise control of skeletal muscle contraction and therefore voluntary movement.  The correct order of a signal being transmitted across a neuromuscular junction is the following: Neuron-neurotransmitter-receptor protein-motor end plate.

Anonymous · Answer

Arrival of end plate potential, acetycholine release, action potential, binding of acetycholinesterase to it's substrate. Hope this helps!:)

Anonymous · Answer

Arrival of end plate potential—acetylcholine release—action potential—binding of acetylcholinesterase to its substrate.

Anonymous · Answer

I think the answer would be d

Anonymous · Answer

Neuron—receptor protein—neurotransmitter—motor end plate

Anonymous · Answer

Binding of acetylcholinesterase to its substrate-acetylcholine release-arrival of action potential-end plate potential.

Anonymous · Answer

The general sequence looks something like this.arrival of action potential  followed by acetylcholine release which creates an  end plate potential followed by  binding of acetylcholinesterase to its substrate and then the transmission happens.

Anonymous · Answer

For the purposes of this discussion, a neuromuscular junction is a synapse between a motor neuron and a skeletal muscle. The correct order of a signal being transmitted across a neuromuscular junction is as follows:1. The brain must first send the signal to the muscle that it must move.2. The muscle must then be stimulated by a motor neuron. In other words, the stimulatory impulse must travel from the motor neuron  to the muscle via the synapse. If the command or signal is correctly sent and received via the neuromuscular junction, the muscle will move otherwise the muscle will not move as the brain signal indicated.

Anonymous

What is the correct order of a signal being transmitted across a neuromuscular junction?

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