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Phosphofructokinase is an allosteric enzyme that catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate, an

Phosphofructokinase is an allosteric enzyme that catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate, an early step of glycolysis. In the presence of oxygen, an increase in the amount of ATP in a cell would be expected to  inhibit the enzyme and thus increase the rates of glycolysis and the citric acid cycle

4 Answers

E
Everardo Feil

Feb 20, 2025

Phosphofructokinase is an allosteric enzyme that catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate, an early step of glycolysis. In the presence of oxygen, an increase in the amount of ATP in a cell would be expected to  inhibit the enzyme and thus increase the rates of glycolysis and the citric acid cycleExplanation:Phosphofructokinase is also a regulatory enzyme of glycolysis. It is inhibited allosterically by elevated levels of ATP, which act as an energy-rich signal indicating an abundance of high-energy compounds.Elevated levels of citrates also inhibits it. While it is allosterically activated by AMP, which signals that the nergy stores are depleted.... Show More
E
Everardo Feil

Feb 20, 2025

An increase in the amount of ATP in a cell would be expected to inhibit the enzyme and thus slow the rates of glycolysis and the citric acid cycle.... Show More
E
Everardo Feil

Feb 20, 2025

I believe in the presence of oxygen, an increase in the amount of ATP in a cell would be expected to inhibit the enzyme and therefore, slow the rates of glycolysis and the citric acid cycle. Phosphofructokinase is and enzyme that phosphorylates fructose 6 phosphate in glycolysis. It is an important control enzyme in the regulation of cellular respiration. It is inhibited by ATP and is an allosteric enzyme. ... Show More
E
Everardo Feil

Feb 20, 2025

Phosphofructokinase is an allosteric enzyme that catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate. This a an early reaction in the glycolysis pathway that is a regulatory step in the pathway. An increase int he amount of ATP in the cell might cause decrease in the amount of phosphofructokinase enzyme by a process called feedback inhibition. Glycolysis process is regulated at various steps in which conversion of fructose 6-phosphate to fructose 1,6-bisphosphate is one of the regulatory step. In the presence of oxygen, an increase in the amount of ATP in a cell would be expected to INHIBIT THE PHOSPHOFRUCTOKINASE ENZYME AND SLOWS THE RATE OF GLYCOLYSIS.... Show More

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